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Diethyl Ether, Anhydrous, ACS Reagent, ≥99.0%: Unveiling the Purity and Versatility

Welcome to the comprehensive guide on ‘diethyl ether, anhydrous, ACS reagent, ≥99.0%’. In this detailed exploration, we’ll delve into the characteristics, applications, handling, and safety considerations of this versatile chemical compound. From its chemical properties to its industrial applications, we’ll uncover the multifaceted nature of diethyl ether.

Understanding Diethyl Ether, Anhydrous, ACS Reagent

Diethyl ether, anhydrous, ACS reagent, ≥99.0%, is a colorless, highly volatile liquid with a characteristic odor. It is commonly known simply as “ether.” This compound is synthesized through the acid-catalyzed dehydration of ethanol. Its molecular formula is C4H10O, and it has a molecular weight of 74.12 g/mol.

Diethyl ether, anhydrous, ACS reagent, ≥99.0% is a highly flammable, colorless liquid with a sweet, ethereal odor. It is a common laboratory solvent and has a wide variety of applications in chemistry, biology, and medicine.

Here is some information about diethyl ether, anhydrous, ACS reagent, ≥99.0%:

  • Chemical formula: (C2H5)2O
  • CAS number: 60-29-7
  • Molecular weight: 74.08 g/mol
  • Density: 0.713 g/mL
  • Melting point: -116.2 °C
  • Boiling point: 34.6 °C
  • Flash point: -40 °C
  • Autoignition temperature: 175 °C
  • Vapor pressure: 442 mmHg (20 °C)
  • Solubility in water: 6.7 g/L (20 °C)


  • Diethyl ether is a very volatile liquid and evaporates readily at room temperature.
  • It is a good solvent for a wide variety of organic compounds, including fats, oils, waxes, and resins.
  • It is also miscible with water to a limited extent.
  • Diethyl ether is a flammable liquid and should be handled with care. It can form explosive peroxides when exposed to air and light for extended periods.


  • Diethyl ether is a common laboratory solvent and is used in a wide variety of chemical reactions.
  • It is also used in the extraction of fats and oils from food products.
  • Diethyl ether is a component of some starting fluids and is used as a refrigerant in some applications.
  • It is also used as a topical anesthetic in some medical applications.


  • Diethyl ether is a flammable liquid and should be handled with care.
  • It should be stored in a cool, dry place away from heat and light.
  • It is important to wear appropriate personal protective equipment, such as gloves, safety glasses, and a respirator, when working with diethyl ether.
  • Diethyl ether can form explosive peroxides when exposed to air and light for extended periods. It is important to dispose of diethyl ether properly and to avoid storing it for long periods of time.

Chemical Properties

Diethyl ether is highly flammable and forms explosive peroxides upon exposure to air and light, making proper storage and handling essential. Due to its volatility, it should be stored in a cool, dry place away from direct sunlight. It is sparingly soluble in water but miscible with most organic solvents, making it a versatile solvent in various chemical reactions and extractions.

Applications in Laboratory Settings

In laboratory settings, diethyl ether, anhydrous, ACS reagent, finds wide applications as a solvent for Grignard reagents, azeotropic distillation, and extraction of natural products. Its low boiling point (34.6°C) makes it particularly suitable for use in reflux setups and rotary evaporators, facilitating efficient and precise chemical reactions and extractions.

Industrial Applications

Beyond laboratory use, diethyl ether is utilized in various industrial processes, including the production of cellulose acetate and as a solvent in the manufacture of pharmaceuticals and perfumes. Its role in organic synthesis and as a starting material for the synthesis of other compounds underscores its significance in chemical industries.

Safety Considerations and Handling

Given its flammability and propensity to form explosive peroxides, meticulous observance of safety protocols is essential when handling diethyl ether. Adequate ventilation, equipment grounding, and storage in tightly sealed containers with proper labeling are imperative. Moreover, precautions should be taken to minimize exposure to potential ignition sources, ensuring a safe working environment.

Environmental Impact

While diethyl ether itself is not considered highly toxic, its combustion products, including carbon monoxide and carbon dioxide, pose risks to human health and the environment. Proper disposal methods should be followed to minimize environmental impact, ensuring the safety of both individuals and the ecosystems in which it is utilized or disposed of.

Additional Resources and References

For further information on diethyl ether, anhydrous, ACS reagent, and its applications, consider exploring the following resources:

  1. Sigma-Aldrich – Diethyl Ether, Anhydrous, ACS Reagent, ≥99.0%
  2. PubChem – Diethyl Ether


In conclusion, diethyl ether, anhydrous, ACS reagent, ≥99.0%, is a versatile solvent with numerous applications in laboratory and industrial settings. Its unique chemical properties, including volatility and solubility characteristics, make it indispensable for various processes. However, its flammability and potential hazards necessitate careful handling and adherence to safety guidelines. By understanding its properties and applications, researchers and industrial professionals can harness the potential of diethyl ether while ensuring safety and environmental responsibility.